Woodard GA, Encarnacion B, Downey JR, et al. Probiotics improve outcomes after Roux-en-Y gastric bypass surgery: a prospective randomized trial. J Gastrointest Surg 2009 Jul;13(7):1198-1204.
PMID: 19381735
doi 10.1007/s11605-009-0891-x
http://www.springerlink.com/content/m21j21645701k911/
http://www.springerlink.com/content/m21j21645701k911/fulltext.html http://www.springerlink.com/content/m21j21645701k911/fulltext.pdf
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J Gastrointest Surg. 2009 Jul;13(7):1198-204. Epub 2009 Apr 18.
Probiotics improve outcomes after Roux-en-Y gastric bypass surgery: a prospective randomized trial.
Woodard GA, Encarnacion B, Downey JR, Peraza J, Chong K, Hernandez-Boussard T, Morton JM.
Department of Surgery, Surgery Center for Outcomes Research and Evaluation, Stanford University School of Medicine, Stanford, CA, USA.
INTRODUCTION: Roux-en-Y gastric bypass (RNYGB) surgery offers an effective and enduring treatment for morbid obesity. Gastric bypass may alter gastrointestinal (GI) flora possibly resulting in bacterial overgrowth and dysmotility. Our hypothesis was that daily use of probiotics would improve GI outcomes after RNYGB. METHODS: Forty-four patients undergoing RNYGB were randomized to either a probiotic or control group; 2.4 billion colonies of Lactobacillus were administered daily postoperatively to the probiotic group. The outcomes of H(2) levels indicative of bacterial overgrowth, GI-related quality of life (GIQoL), serologies, and weight loss were measured preoperatively and at 3 and 6 months postoperatively. Categorical variables were analyzed by chi(2) test and continuous variables were analyzed by t test with a p
PMID: 19381735