Takeuchi F, McGinnis R, Bourgeois S, et al. A Genome-Wide Association Study Confirms VKORC1, CYP2C9, and CYP4F2 as Principal Genetic Determinants of Warfarin Dose. PLoS Genetics 2009 Mar 20;5(3):e1000433
http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1000433
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PLoS Genet. 2009 Mar;5(3):e1000433. Epub 2009 Mar 20.
A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose.
Takeuchi F, McGinnis R, Bourgeois S, Barnes C, Eriksson N, Soranzo N, Whittaker P, Ranganath V, Kumanduri V, McLaren W, Holm L, Lindh J, Rane A, Wadelius M, Deloukas P.
Wellcome Trust Sanger Institute, Hinxton, UK.
We report the first genome-wide association study (GWAS) whose sample size (1,053 Swedish subjects) is sufficiently powered to detect genome-wide significance (p
PMID: 19300499